Genetic Skin Diseases

Single gene disorders:

Single gene disorders are caused by DNA changes in one particular gene and often have predictable inheritance patterns. Genetic skin diseases center is a leading center for the diagnosis and management of people with genetic skin disorders. We treat a wide variety of skin diseases, including:

• Ichthyosis (thickened, dry and scaly skin)
• Palmoplantar keratoderma (thickened skin on the palms of the hand and soles of the feet)
• Ectodermal dysplasia (a group of disorders affecting a combination of hair, nails, teeth or sweating)
• Pachyonychia congenita (a rare genetic skin disease causing thickened nails and skin problems). 

Single Gene-Pair Inheritance:

Single gene-pair inheritance happens once an attribute is coupled to at least one gene-pair that consists of 2 alleles. This can be also mentioned as a Mendelian inheritance. A gene is one a part of the gene pair. One gene is inheritable from the father, and one is inheritable from the mother.

When a particular gene is understood to cause a sickness, we consult with it as a single gene disorder or a Mendelian disorder. As an example, you will have detected of monogenic disorder, erythrocyte sickness, Fragile X syndrome, genetic defect, or Huntington sickness. These are all samples of single gene disorders. As a rule, single gene disorders are not quite common. As an example, only 1 in a pair of, 500 folks are born with a monogenic disease. There are varieties of inheritance patterns of single gene disorders that are predictable once you understand what they are.

Types of Genetic Skin Diseases:

·         Single gene inheritance

·         Multifactorial inheritance

·         Chromosome abnormalities

·         Mitochondrial inheritance

·         Ichthyoids

·         Ectodermal dysplasia

For more information: https://skin-body.dermatologymeeting.com/

Name: Joanna Jae | Email id: skincare@memeetings.com